Idebenone CAS 58186-27-9
Idebenone is an organic compound with the chemical name: 6-(10-hydroxydecyl)-2,3-dimethoxy-5-methyl-1,4-benzoquinone. It is a structural analogue of coenzyme Q10 and is developed by Takeda Pharmaceuticals as a drug for the treatment of cognitive diseases such as Alzheimer??s disease.
Idebenone has an activating effect on mitochondrial function, improves brain metabolism and brain dysfunction, and can increase the utilization rate of glucose in the brain and promote the generation of ATP; it improves the metabolism of the neurotransmitter 5-hydroxytryptamine in the brain and has a strong antioxidant and free radical scavenging effect. In clinical practice, it is mainly used to treat many central nervous system degenerative diseases related to oxidative stress, such as Parkinson??s disease, Alzheimer??s disease, multi-infarct dementia, local cerebral anemia and brain failure, etc. It is also used to treat Friedreich??s ataxia. It can also be used in cosmetic formulas, with cosmetic efficacy such as scavenging free radicals, inhibiting lipid peroxidation, inhibiting inflammation, inhibiting DNA damage, light protection, and reducing pigmentation.
Idebenone CAS 58186-27-9
| Idebenone Basic information |
| Product Name: | Idebenone |
| Synonyms: | cv 2619 idebenone;Daruma??Mnesis;2,5-Cyclohexadiene-1,4-dione, 5,6-dimethoxy-2-(10-hydroxydecyl)-3-methyl-;6-(10-Hydroxydecyl)ubiquinone;2-(10-Hydroxydecyl)-5,6-dimethoxy-3-methyl-2,5-cyclohexadiene-1,4-dione;2-(10-hydroxydecyl)-5,6-dimethoxy-3-methyl-p-benzoquinone;IDEBENONE(P);2-(10-Hydroxydecyl)-5??6-dimethoxy-3-methyl-2??5-cyclohexadienPl??4-dione |
| CAS: | 58186-27-9 |
| MF: | C19H30O5 |
| MW: | 338.44 |
| EINECS: | 1308068-626-2 |
| Product Categories: | Aromatics;API;Other APIs;AP;Anthraquinones, Hydroquinones and Quinones;Cnbio;Intermediates & Fine Chemicals;Pharmaceuticals;58186-27-9 |
| Mol File: | 58186-27-9.mol |
 |
|
| Idebenone Chemical Properties |
| Melting point | 52-550C |
| Boiling point | 497.3??45.0 ??C(Predicted) |
| density | 1.08??0.1 g/cm3(Predicted) |
| storage temp. | room temp |
| solubility | Soluble in DMSO (up to 25 mg/ml). |
| form | Solid |
| pka | 15.20??0.10(Predicted) |
| color | Orange |
| Merck | 14,4888 |
| Stability: | Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20??C for up to 3 months. |
| InChI | InChI=1S/C19H30O5/c1-14-15(12-10-8-6-4-5-7-9-11-13-20)17(22)19(24-3)18(23-2)16(14)21/h20H,4-13H2,1-3H3 |
| InChIKey | JGPMMRGNQUBGND-UHFFFAOYSA-N |
| SMILES | C1(=O)C(OC)=C(OC)C(=O)C(C)=C1CCCCCCCCCCO |
| LogP | 3.490 (est) |
| CAS DataBase Reference | 58186-27-9(CAS DataBase Reference) |
| Safety Information |
| Hazard Codes | Xi |
| WGK Germany | 3 |
| RTECS | GU5290000 |
| HS Code | 2933399990 |
Related Products
Benzothiazoles are a class of chemical compounds characterized by a fused benzene and thiazole ring. They exhibit a broad spectrum of applications, particularly as antioxidants in rubber and plastic industries, enhancing product longevity and performance. Additionally, benzothiazoles serve as key intermediates in the synthesis of pharmaceuticals, contributing to the development of life-saving drugs. Recognized for their stability and reactivity, these compounds are integral to advancing material science and healthcare solutions.
Product name:HYDROXYPROPYL GUAR HYDROXYPROPYLTRIMONIUM CHLORIDE
Purity:99%
Appearance:Light Yellow Powder
Package:Customized according to customer needs.
Sample:Available
Chemical Name: Potassium Castorate
CAS No.: 8013-05-6
Molecular Formula: C57H107K3O12
Molecular Weight: 1101.74718
Appearance: Yellow Liquid
Butylated Hydroxytoluene (BHT) is a synthetic phenolic antioxidant commonly added to foods, cosmetics, and packaging to prevent the oxidation of fats and oils, thereby extending their shelf life. It is also used as a preservative in a variety of products, including rubber, petroleum products, and animal feed. BHT is recognized for its effectiveness in maintaining nutrient levels, color, flavor, and odor in food products . It is known to have a melting point of 69-71??C, a boiling point of 265??C, and is soluble in ethanol, acetone, and benzene, but not in water, glycerin, or propylene glycol . BHT is also used in some dietary supplements due to its antioxidant properties . However, it is important to handle BHT with care, as it can cause skin irritation and is considered harmful if swallowed .
Silicone oil, known for its chemical designation as dimethicone or polydimethylsiloxane, is a synthetic polymer with a backbone of alternating silicon and oxygen atoms, creating a highly versatile and stable compound. It is renowned for its exceptional lubricating properties, heat resistance, and non-toxic nature, making it a staple in various industries, including cosmetics, automotive, and aerospace.
This hydrophobic, non-volatile oil is valued for its ability to provide a smooth, non-greasy feel and to form stable emulsions with other ingredients. In personal care products, silicone oil is used to impart a silky texture, reduce friction on the skin, and create a protective barrier against environmental stressors without clogging pores.
Silicone oil’s chemical inertness and resistance to oxidation contribute to its long shelf life and stability in formulations. It is also appreciated for its compatibility with a wide range of substances, allowing for the creation of multifunctional products.
In summary, silicone oil is a reliable and multifaceted ingredient, offering a combination of performance, safety, and sensory benefits. Its use in a variety of applications reflects its versatility and enduring appeal in the marketplace.
Chemical Name: Ashwagandha Extract
Synonyms: Withania somnifera, ext.; Withania Somnefera Extract
CAS: 90147-43-6
Appearance: Brown
1-Octanol, also known as Capryl alcohol or n-Octanol, is a clear, colorless liquid with a characteristic waxy odor. It is an alcohol with eight carbon atoms in its chain, making it a part of the aliphatic alcohol family. This compound is poorly soluble in water but is miscible with ethanol, diethyl ether, and chloroform . It has a melting point of approximately -15??C and a boiling point of around 196??C . 1-Octanol is used in the production of esters, plasticizers, and as a solvent or intermediate in the synthesis of various organic compounds. It also finds application in the fragrance industry as a fixative in perfumes and can be used in the formulation of flavor and scent compositions . It is important to note that 1-Octanol is flammable and should be handled with care, storing it away from sources of ignition and heat .
Silicones are a family of synthetic polymers known for their versatility and stability. They are heat-resistant, non-toxic, and have excellent electrical insulation properties. Commonly used in various industries such as construction, automotive, aerospace, and personal care products, silicones offer a wide range of applications from sealants and adhesives to lubricants and medical devices. Their resistance to extreme temperatures and weathering makes them a preferred choice for many high-performance applications.
Chemical Name: STODDARD SOLVENT
CAS No.: 64742-88-7
Appearance: Colorless or Light Yellow Liquid
N,N-Dimethylaniline is an organic compound with amine and methyl groups attached to a benzene ring. It is a colorless liquid with a characteristic amine odor. This compound is primarily used as a chemical intermediate in the synthesis of dyes, pigments, and polymers. Its reactivity makes it a valuable building block in the production of various organic compounds, particularly in the pharmaceutical and chemical industries.
Chemical Name: Quercetin-3-O-sophoroside
CAS No.: 18609-17-1
Molecular Formula: C27H30O17
Molecular Weight: 626.52
Chemical Name: Zinc citrate
Synonyms: Zinc citrate trihydrate
CAS No.: 546-46-3
Molecular Formula: C6H8O7Zn
Molecular Weight: 257.5
Appearance: White powder
