Polyglutamic acid CAS# 25513-46-6

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Polyglutamic acid (CAS 25513-46-6) is usually in the form of white powder.
Polyglutamic acid is a high molecular compound with good water solubility and biocompatibility.
It has many excellent properties, such as water retention, plant growth promotion, and improved fertilizer utilization. In the agricultural field, it can be used as a fertilizer enhancer, water retainer, etc., which helps to improve the fertility and water retention capacity of the soil and promote the growth and development of crops. For example, adding it to fertilizer can reduce fertilizer loss and improve the effect of fertilizer.
In the field of cosmetics, polyglutamic acid is also used, because its moisturizing properties can be used in skin care products.

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Polyglutamic acid CAS# 25513-46-6

Polyglutamic acid Basic information

Product Name:	Polyglutamic acid
Synonyms:	POLY-L-GLUTAMIC ACID 15’000-50’000 SODIUM SALT;POLY-L-GLUTAMIC ACID 2’000-15’000;POLY-L-GLUTAMIC ACID 50’000-100’000 SODIUM SALT;L-GLU-(L-GLU)N-L-GLU;glutamicacidpolymer;POLY-L;gamma-poly(L-glutamic acid) macromolecule;G-poly glutamic acid
CAS:	25513-46-6
MF:	C5H9NO4
MW:	147.13
EINECS:	200-293-7
Product Categories:	Amino Acids;Homopolymers;Polyamino Acids;25513-46-6
Mol File:	25513-46-6.mol

Polyglutamic acid Chemical Properties

storage temp.	?20??C
InChI	InChI=1/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/t3-/s3
InChIKey	WHUUTDBJXJRKMK-ZJPLZJKBNA-N
SMILES	[C@@H](N)(C(=O)O)CCC(=O)O \|&1:0,r\|

Safety Information

WGK Germany	3
RTECS	MA1700000
F	3-10

MSDS Information

Provider	Language
SigmaAldrich	English

Polyglutamic acid Usage And Synthesis

Description	Polyglutamic acid (PGA), a poly amino acid produced by Bacillus spp. is a naturally occurring anionic, water-soluble, biodegradable, non-toxic, viscous, edible biopolymer containing D and L-glutamic acid residues with different industrial applications.
Uses	Polyglutamic acid is commonly used in cosmetics as a powerful humectant for moisturising the skin. It is ideal for people with dry or dehydrated skin and may help to reduce the appearance of fine lines and wrinkles. Polyglutamic acid is also used in the food industry and has the ability to improve taste and flavour. In addition, Polyglutamic acid is an environmentally friendly biomaterial that can be used as a drug carrier/delivery agent and as a contrast agent.
Definition	ChEBI: A macromolecule composed of repeating gamma-linked L-glutamyl units.
Preparation	The Preparation method of Polyglutamic acid is as follows??poplar sawdust was used to produce Polyglutamic acid. Poplar sawdust was treated with acid and then hydrolyzed with cellulose. The enzymatic hydrolysate was used to produce Polyglutamic acid. Through single factor and orthogonal experiments, the optimum enzymatic conditions were determined as follows: solid-liquid ratio 1:5, enzyme amount 22 FPU/g, pH 5.0 and 53 min. Under the enzymatic hydrolysate medium, the Polyglutamic acid yield reached 30.87 ?? 0.44 g/L, which was 5.11% higher than that in glucose medium (29.37 ?? 0.43 g/L). In addition, the amount of glucose added to the medium was reduced, which realized the comprehensive utilization of various sugars in sawdust enzymatic hydrolysate.
Application	Polyglutamic acid is considered a promising bio-based chemical and is already widely used in the food, medical, and wastewater industries due to its biodegradable, non-toxic, and non-immunogenic properties.
benefits	The primary benefit of polyglutamic acid is its impressive ability to hydrate skin. Because it??s a polymer, it forms a flexible, smooth, moisture-binding film on skin??s surface. This film helps skin keep moisture in its surface layers, even in conditions of low humidity, making polyglutamic acid an effective humectant. In addition to its abilities to aid skin in moisture retention, polyglutamic acid soothes and helps increase the production of natural moisturizing factors (NMF) in skin, which contributes to having a healthier barrier and balanced hydration. Polyglutamic acid hydrates skin but also performs other roles as well including wrinkle reduction, balancing the effects of chronic sun exposure and enhancing wound healing.
Side effects	Polyglutamic acid is generally considered safe and allergic reaction side effects are rare, which may result in itching, swelling, redness, burning sensation or blisters. Before applying Polyglutamic acid to your face, you can perform a patch test to ensure that you are tolerating this ingredient well.
Toxicology	This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher