Octocrylene CAS#6197-30-4
Octocrylene is an organic compound widely recognized for its potent UV-filtering properties, making it an essential ingredient in sunscreens and other skincare products designed to protect the skin from harmful ultraviolet radiation. With the chemical name 2-(4-Methylbenzyl)-2H-benzotriazole-5-methyl, octocrylene is a stable and photostable molecule that provides broad-spectrum protection against both UVA and UVB rays.
This oil-soluble chemical is valued for its ability to absorb UV radiation effectively, converting it into heat without causing skin irritation or staining clothes. Octocrylene is often used in combination with other UV filters to enhance the sun protection factor (SPF) of formulations, ensuring a balanced and comprehensive defense against sun damage.
As a lipophilic compound, octocrylene is compatible with various cosmetic and dermatological formulations, contributing to the development of lightweight, non-greasy sunscreens. Its chemical structure allows for a high degree of safety and efficacy, making it suitable for a wide range of skin types, including sensitive skin.
In summary, octocrylene is a reliable and efficient UV filter, pivotal in the formulation of modern sunscreens that offer advanced protection against the sun’s harmful effects while maintaining skin comfort and product aesthetics.
| Octocrylene Chemical Properties |
| Melting point | -10 ??C (lit.) |
| Boiling point | 218 ??C/1.5 mmHg (lit.) |
| density | 1.051 g/mL at 25 ??C (lit.) |
| vapor pressure | 0Pa at 25?? |
| refractive index | n20/D 1.567(lit.) |
| Fp | >230???F |
| storage temp. | 15-25??C |
| solubility | Chloroform (Slightly), Methanol (Sparingly) |
| form | Oil |
| color | Colourless to Light Yellow |
| Merck | 14,6756 |
| InChIKey | FMJSMJQBSVNSBF-UHFFFAOYSA-N |
| LogP | 6.1 at 23?? |
| CAS DataBase Reference | 6197-30-4(CAS DataBase Reference) |
| EPA Substance Registry System | 2-Ethylhexyl 2-cyano-3,3-diphenylacrylate (6197-30-4) |
| Absorption | uv max: 303 nm |
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Polyhexamethylene guanidine hydrochloride, often abbreviated as PHMG-HCl, is a high molecular weight polymeric biguanide compound known for its potent antimicrobial properties. With a chemical structure that features a long chain of methylene groups bridged by guanidine units, PHMG-HCl is effective against a broad spectrum of microorganisms, including bacteria, viruses, and fungi.
This hydrochloride salt form of PHMG is highly soluble in water and is commonly used in various applications due to its non-irritant and non-toxic nature to human skin and mucous membranes. It is widely recognized for its ability to form a colorless and odorless solution, making it an ideal choice for use in personal care products, medical disinfectants, and water treatment processes.
The versatility of PHMG-HCl lies in its cationic nature, which allows it to bind to negatively charged microbial cell walls, disrupting their integrity and leading to cell death. This mechanism of action contributes to its effectiveness as a preservative and disinfectant. Moreover, its substantivity, or the ability to adhere to surfaces, enhances its long-lasting antimicrobial activity.
In summary, Polyhexamethylene guanidine hydrochloride is a reliable and efficient antimicrobial agent, pivotal in industries where hygiene and cleanliness are paramount, offering a safe and sustainable solution for microbial control.
