Allicin CAS 539-86-6

Huperzine A is a natural plant extract. Compared with similar AD treatment drugs approved by the US FDA, Huperzine A has a unique chemical structure and has extremely high selectivity to inhibit acetylcholinesterase in the brain and enhance cholinergic in the brain. function of neurons. In addition, Huperzine A has obvious effects on improving memory and improving cognitive ability.

Huperzine A has a small relative molecular weight, high lipid solubility, and is easy to pass through the blood-brain barrier. After entering the central nervous system, it is mostly distributed in the frontal lobe, temporal lobe, hippocampus and other parts of the brain. Its pharmacological effects have multiple targets. In addition to inhibiting the activity of acetylcholinesterase, it can also antagonize oxidative stress and apoptosis induced by ??-amyloid peptide (A??), hydrogen peroxide and other neurotoxins, by activating the protein kinase C (PKC) signal transduction pathway. Activation of ??-secretase promotes the decomposition of ??-amyloid precursor protein (APP) in a non-amyloidogenic manner to produce sAPP??, reducing A??-mediated toxicity, while sAPP?? can effectively promote cell proliferation, axonal growth, and protect nerves. cell.

Arbutin, a derivative of hydroquinone, is a naturally occurring compound extracted primarily from the bearberry plant (Arctostaphylos uva-ursi). It is renowned in the skincare industry for its skin lightening properties, making it a popular ingredient in cosmetic products designed to reduce hyperpigmentation and even out skin tone.

Chemically, arbutin is ??-glucosiduronic acid of hydroquinone, with the molecular formula C12H12O7. Its mechanism of action involves the inhibition of tyrosinase, a key enzyme in the melanin biosynthesis pathway. By reducing melanin production, arbutin effectively lightens the skin without the risk of irritation often associated with hydroquinone.

Arbutin is valued for its safety profile, as it is considered less irritating and more stable compared to other skin lightening agents. It is also known for its antioxidant properties, which contribute to its skin brightening effects and overall skin health benefits.

In summary, arbutin is a reliable and gentle alternative for skin lightening, offering a natural approach to reducing pigmentation issues while promoting a more radiant and even complexion. Its use in skincare formulations is favored for its efficacy and mildness, making it suitable for various skin types.

Puerarin, also known as pueraria flavonoids, is a kind of flavonoid glycoside extracted from the roots of Pueraria alba or Pueraria thomsonii and is also one of the main effective ingredients of Pueraria lobata. That Pueraria lobate was used to treat diseases has already been recorded in China??s ancient medical books such as Shen Nong??s Materia Medica, Treatise on Miscellaneous Diseases and Medical Dictionary.
Kanzu root is widely distributed in our country and of rich resources. It has been reported that puerarin could be extracted from Pueraria lobata (Wild.) Ohwi, Radix Pueraria thomsonii, Pueraria omeiensiswanget Tang, Pueraria edulis Pamp and Pueraria phaseoloides, but the content of puerarin differs.
Pueraria has a great value for nutrition and medicine and was considered the south ginseng of China. Puerarin has been widespread concerned over our country for its use of food and medicine in recent years.