5-BROMO-4′-CHLOROSALICYLANILIDE Cas 3679-64-9
$199.00
Chemical Name: 5-BROMO-4′-CHLOROSALICYLANILIDE
CAS No.: 3679-64-9
Molecular Fomula: C13H9BrClNO2
Molecular weight:326.57
Appearance: Transparent light yellow to brown liquid
Assay: ≥98%
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5-Bromo-4′-Chlorosalicylanilide (CAS 3679-64-9) Technical Guide
Table of Contents
1. Product Specifications & Comparative Analysis
Parameter | Specification | Industry Equivalent |
---|---|---|
Chemical Name | 5-Bromo-4′-chlorosalicylanilide | Salifungin |
CAS No. | 3679-64-9 | N/A |
Molecular Formula | C13H9BrClNO2 | C13H9BrClNO2 |
Molecular Weight | 326.57 g/mol | 320-330 g/mol |
Melting Point | 245-247°C | 240-250°C |
LogP | 4.13 | 3.8-4.3 |
HS Code | 29242990.90 | 292429**** |
2. Functional Applications
This halogenated salicylanilide derivative serves as:
- Antimicrobial agent precursor for pharmaceutical formulations
- Intermediate in organic synthesis of antifungal compounds
- Research chemical for structure-activity relationship studies
- Key component in specialty polymer synthesis
3. Operational Guidelines
Handling Protocols
- Store in airtight containers at 2-8°C protected from light
- Use nitrogen atmosphere for moisture-sensitive reactions
- Employ personal protective equipment (PPE) including neoprene gloves
Reaction Optimization
- Optimal coupling efficiency achieved at 60-80°C in DMF
- Maintain pH 6.5-7.5 for aqueous phase reactions
4. Implementation Case Studies
Case A: Antifungal Drug Development
Used as lead compound in discovery of novel azole antifungals, demonstrating 92% inhibition against Candida spp. at 50μM concentration.
Case B: Polymer Additive Synthesis
Enhanced thermal stability (ΔTg +18°C) in polycarbonate blends when incorporated at 0.5-1.2% w/w.
5. Client Success Stories
Pharmaceutical Innovator (Shanghai)
Reduced lead compound development time by 40% through optimized bromination protocols using this intermediate.
European Research Consortium
Enabled synthesis of 15 novel antifungal analogs with improved bioavailability profiles (Frel >85%).
6. Commercial Inquiry
Request technical specifications or bulk pricing:
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