2-Tetrahydrofuroic Acid CAS 16874-33-2

Description

2-Tetrahydrofuroic acid Details
Chemical Name: 2-Tetrahydrofuroic acid
Synonyms: Tetrahydrofurioic Acid; Tetrahydro-2-furoic Acid; T2F; THFC; THFAC; 2-THFA??tetrahydrofuran-2-carboxylic acid; 2-tetrahydrofuoic acid; 2-tetrahydrofuoic acid
CAS No.: 16874-33-2
Molecular Formula: C5H8O3
Molecular Weight: 116.12
Molecular?Structure:

Appearance:?Colorless?to?light?yellow?liquidAssay: 99%
Typical?Properties

Melting point
21??C

Boiling point
128-129???C13?mm Hg(lit.)

Density
1.209?g/mL?at 25???C(lit.)

Water Solubility
soluble

Appearance
Liquid

Colour
Transparent yellow to brown

Refractive index
n20/D 1.46 (lit.)

2-Tetrahydrofuroic acid Usage
2-Tetrahydrofuran-2-carboxylicacid (2-THFA) can be split into (R)-2-THFA and (S)-2-THFA. Chiral 2-tetrahydrofurancarboxylicacid is an important ligand synthon in asymmetric synthesis reactions. Among them, (R)-2-THFA is an important intermediate for the synthesis of the antibiotic furopenem, which can be used as an antagonist of the antigen VLA-4, and is also a chiral resolution agent for an important intermediate of the super flu drug Xofluza; (S)-2-THFA is the main raw material for the preparation of the chiral auxiliary (S)-acetyltetrahydrofuran, a raw material for the preparation of cephalosporin antibiotic intermediates, and an important intermediate for the preparation of the hormone LHRH that stimulates hormone release.
Packaging and Shipping
200kg/drum
2-Tetrahydrofuroic acid Storage
It?should?be?stored?in?a?clean,?dry?and?cool?place,?preventing?from?sunlight,?rain.