2-Fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)Methyl)benzoic Acid Cas 763114-26-7
Chemical Name: 2-fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)Methyl)benzoic acid
CAS No.: 763114-26-7
Molecular Fomula: C16H11FN2O3
Molecular weight: 298.27
Appearance: White to off white powder
Assay：99 % min
2-Fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)Methyl)benzoic Acid (CAS 763114-26-7) Comprehensive Guide
Table of Contents
- Product Specifications & Comparative Analysis
- Applications & Industrial Use Cases
- Synthesis Case Study: PARP Inhibitor Development
- Client Success Stories
- Technical Consultation & Ordering
Product Specifications & Comparative Analysis
| Parameter | Specification | Competitor A | Competitor B |
|---|---|---|---|
| CAS Number | 763114-26-7 | N/A | N/A |
| Purity | ≥98% (HPLC) | ≥95% | ≥97% |
| Storage | 2-8°C (desiccated) | Ambient | 2-8°C |
| Solubility | DMSO, DMF | DMSO only | DMF limited |
Key Applications in Pharmaceutical R&D
This fluorinated benzoic acid derivative serves as critical intermediate in:
- PARP (Poly ADP-ribose polymerase) inhibitor synthesis
- Oncology drug discovery programs
- DNA repair mechanism studies
- Radio-sensitizing agent development
Synthesis Case Study: PARP1 Inhibitor Development
| Stage | Application | Yield Improvement |
|---|---|---|
| Intermediate Preparation | Core structure functionalization | 22% increase vs traditional methods |
| Final Coupling | Selective methyl group activation | 15% higher efficiency |
Verified Client Implementations
Case 1: Top 10 Pharma Company (2023)
Application: BRCA-mutant cancer drug candidate scale-up
Results: Achieved 99.2% purity at 50kg batch scale
Case 2: Biotech Startup (2024)
Application: Novel PARP1/2 dual inhibitor development
Results: Reduced synthesis steps from 8 to 5
Technical Support & Order Inquiry
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