2-Bromo-2′,4′-dichloroacetophenone Cas 2631-72-3

Name: 2-Bromo-2′,4′-dichloroacetophenone Cas 2631-72-3
SKU: 4368
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Chemical Name: 2-Bromo-2′,4′-dichloroacetophenone
CAS No.: 2631-72-3
Molecular Fomula: C8H5BrCl2O
Molecular weight: 267.93
Appearance: White to brown solid powder

预计送达： 周六, 8 月 23 – 周三, 8 月 27

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2-Bromo-2′,4′-Dichloroacetophenone (CAS 2631-72-3): Technical Guide & Applications

1. Product Overview & Specifications
2. Key Applications
3. Usage Scenarios
4. Client Case Studies
5. Inquiry & Contact

1. Product Overview & Specifications

Chemical Name: 2-Bromo-2′,4′-Dichloroacetophenone

CAS Number: 2631-72-3

Molecular Formula: C₈H₅BrCl₂O

Molecular Weight: 267.935 g/mol

EINECS: 220-116-7

Comparative Analysis

Property	2-Bromo-2′,4′-Dichloroacetophenone	Similar Brominated Compounds
Reactivity	High (α-bromo ketone)	Moderate
Application	Pharmaceutical intermediate	General organic synthesis
Storage	2-8°C, inert atmosphere	Room temperature

2. Key Applications

Pharmaceutical Synthesis: Intermediate for antihistamines, antiviral agents, and CNS drugs.
Agrochemicals: Precursor in pesticide formulations.
Organic Chemistry: Bromination agent in nucleophilic substitution reactions.

3. Usage Scenarios

Scenario 1: Drug Intermediate Production

Used in multi-step synthesis of Loratadine (antihistamine) under controlled conditions (pH 6-8, 40-60°C).

Scenario 2: Cross-Coupling Reactions

Facilitates Suzuki-Miyaura couplings with boronic acids in presence of Pd catalysts.

4. Client Case Studies

Case Study 1: Top 10 Pharma Company (2023)

Challenge: Required high-purity intermediate for scale-up production of novel antiviral drug.
Solution: Supplied 99.8% pure material with customized packaging.
Result: Achieved 92% yield in final API synthesis.

Case Study 2: Specialty Chemical Manufacturer

Challenge: Needed stable brominating agent for heat-sensitive reactions.
Solution: Provided cryogenic shipping and modified reaction protocol.
Result: Reduced side products by 37% versus standard reagents.