1-Hexadecylamine CAS 143-27-1
Chemical Name: 1-Hexadecylamine
Synonyms 1-Aminohexadecane; Hexyldecylamine; n-Certylamine
CAS No.: 143-27-1
Molecular Formula: C16H35N
Molecular Weight: 241.46
Appearance: White Crystal
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1-Hexadecylamine (CAS 143-27-1) Comprehensive Product Guide
Table of Contents
- 1. Product Overview & Specifications
- 2. Key Applications & Industrial Uses
- 3. Performance Comparison with Similar Amines
- 4. Operational Guidelines & Safety Protocols
- 5. Verified Customer Case Studies
- 6. Request Customized Solutions
1. Product Overview & Specifications
1-Hexadecylamine (CAS 143-27-1), also known as cetrimonium amine, is a long-chain primary amine widely used in industrial chemistry. Key parameters:
| Parameter | Value |
|---|---|
| Chemical Formula | C16H35N |
| Molecular Weight | 241.46 g/mol |
| Appearance | White crystalline solid |
| Purity | ≥98% (GC analysis) |
| Melting Point | 46-49°C |
| Solubility | Insoluble in water, soluble in ethanol/chloroform |
| Storage | 2-8°C in airtight container |
2. Key Applications & Industrial Uses
Core Functional Areas:
- Surfactant Intermediate: Cationic precursor for quaternary ammonium compounds
- Corrosion Inhibition: Metal surface treatment in acidic environments
- Pharmaceuticals: Drug delivery vector in lipid nanoparticle formulations
- Cosmetic Chemistry: Emulsion stabilizer in hair conditioners
- Agrochemicals: Adjuvant for pesticide formulations
- Petroleum Additives: Friction modifier in lubricant packages
3. Performance Comparison with Similar Amines
| Parameter | Hexadecylamine | Octadecylamine | Tetradecylamine |
|---|---|---|---|
| Carbon Chain | C16 | C18 | C14 |
| Melting Point | 46-49°C | 53-56°C | 38-41°C |
| Surface Tension | 32 mN/m | 29 mN/m | 35 mN/m |
| Krafft Temperature | 45°C | 50°C | 40°C |
| Cost Efficiency | ★★★★☆ | ★★★☆☆ | ★★★★★ |
4. Operational Guidelines & Safety Protocols
Handling Requirements:
- Use NIOSH-approved respirator when handling powder form
- Maintain ventilation rates ≥15 CFM/sq.ft in processing areas
- Ground all equipment to prevent static discharge
Storage Compatibility:
- Incompatible with strong oxidizers, acids, and halogenated compounds
- Maximum stacking height: 1.8 meters in palletized storage
5. Verified Customer Case Studies
Case 1: Pharmaceutical Delivery System Enhancement
Client: European mRNA Vaccine Producer
Challenge: Required stable lipid nanoparticles with >80% encapsulation efficiency
Solution: Optimized 1-Hexadecylamine concentration at 0.8 mol% in lipid matrix
Outcome: Achieved 92% encapsulation with 6-month stability at 2-8°C
Case 2: Industrial Corrosion Inhibition
Client: Gulf Coast Oil Refinery
Challenge: Reduce pipeline corrosion rates from 0.8 mm/yr to <0.2 mm/yr
Solution: 200 ppm Hexadecylamine-based inhibitor in recirculating system
Outcome: 0.15 mm/yr corrosion rate achieved, extending maintenance intervals by 300%
6. Request Customized Solutions
For technical specifications, bulk pricing, or formulation assistance:
- Email: info@vivalr.com
- Phone: (86) 15866781826
[Request SDS] [Download Technical Dossier] [Schedule Lab Demo]
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