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Urapidil is a sympathetic antihypertensive drug. It acts as ?? 1 ?C adrenoceptor antagonists and 5-HT 1A receptor agonists act. Although the initial report showed that urapidil was also a ?? 2 ?C adrenoceptor agonist, which was not confirmed in later studies, proved that it had no agonist effect in the saphenous vein of dogs and ileum of guinea pigs. With others ?? Unlike 1-adrenoceptor villains, urapidil does not cause response tachycardia, which may be connected to its weak ?? 1-adrenoceptor antagonist activity and its impact on heart vagal drive. Urapidil has actually not been approved by the US Food and drug administration, yet it is offered in Europe.

Urapidil (URA), chemical name is 6-[[3-[4-(2-methoxyphenyl)-1-piperazinyl]propyl]amino]-1,3-dimethyl -2,4(1H,3H)-pyrimidinedione, trade name: ebrantil (ebrantil), synonym: excellent matchi, uracil substituted by phenazine.