L-Menthol CAS #2216-51-5
Menthol, also known as hexahydrothymol, is commonly known as L-menthol, and its scientific name is 5-methyl-2-isopropyl-cyclohexanol. It is a very important cycloterpene alcohol. L-menthol has a characteristic mint aroma and has a cooling effect. Racemic ?C menthol also has a cooling effect, while other isomers have no cooling effect. L-menthol accounts for a large proportion of applications in medicine and health. It can be used as poultice, ointment, analgesic, local anesthetic, cooling agent, antipruritic agent, mouthwash, bactericide, and for the treatment of toothache, Tablets for stomach pain, neuralgia, etc.; the second largest use is spices. L-menthol is a spice in demand among cyclic monoterpene alcohols. It can be used as tobacco spices, used with peppermint oil to prepare toothpaste flavors, and other spices. Toilet water; menthol can also be used as a flavoring agent for a variety of foods, such as candies, chewing gum, cakes, fruit wine, refreshing drinks, etc.
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L-Menthol CAS #2216-51-5
| L-Menthol Basic information |
| Product Name: | L-Menthol |
| Synonyms: | (1R,2S,5R)-(-)-MENTHOL, 99+%, SUBLIMED;L-MENTHOL 99+% NATURAL FCC;L-MENTHOL, 99+%;(1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexanol;Cyclohexanol, 5-methyl-2-(1-methylethyl)-, [1R-(1??,2,5??)]-;(1R,2S,5R)-(L)-Menthol;Mentol Crysta;L-MENTHOL, BP 99+% |
| CAS: | 2216-51-5 |
| MF: | C10H20O |
| MW: | 156.27 |
| EINECS: | 218-690-9 |
| Product Categories: | Inhibitors;Organics;chiral;Biochemistry;Terpenes;Terpenes (Others);for Resolution of Acids;Monocyclic Monoterpenes;Optical Resolution;Synthetic Organic Chemistry;API;2216-51-5 |
| Mol File: | 2216-51-5.mol |
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| L-Menthol Chemical Properties |
| Melting point | 41-45 ??C (lit.) |
| Boiling point | 212 ??C (lit.) |
| alpha | -51 o (589nm, c=10, EtOH) |
| density | 0.89 g/mL at 25 ??C (lit.) |
| vapor pressure | 0.8 mm Hg ( 20 ??C) |
| FEMA | 2665 | MENTHOL RACEMIC |
| refractive index | 1.46 |
| Fp | 200???F |
| storage temp. | Store below +30??C. |
| solubility | 490mg/l |
| form | Crystals or Crystalline Needles |
| pka | 15.30??0.60(Predicted) |
| Specific Gravity | 0.89 |
| color | Colorless to white |
| Odor | at 10.00 % in dipropylene glycol. peppermint cooling mentholic minty |
| Odor Type | mentholic |
| optical activity | [??]22/D 49??, c = 10 in 95% ethanol |
| Water Solubility | insoluble |
| Merck | 14,5837 |
| BRN | 1902293 |
| Dielectric constant | 3.2??Ambient?? |
| Stability: | Stable. |
| InChIKey | NOOLISFMXDJSKH-KXUCPTDWSA-N |
| LogP | 3.15 at 25?? |
| CAS DataBase Reference | 2216-51-5(CAS DataBase Reference) |
| NIST Chemistry Reference | Cyclohexanol, 5-methyl-2-(1-methylethyl)-, [1R-(1?alpha?,2?beta?,5?alpha?)]-(2216-51-5) |
| EPA Substance Registry System | Levomenthol (2216-51-5) |
- 2
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- 95-16-9
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- Benzothiazole
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Cinnamic aldehyde is used as a flavoring agent, ingredient of fragrance in soft drinks, ice creams, dentifrices, pastries, chewing-gum, etc. It can induce both contact urticaria and delayed-type reactions. It can be implicated in contact dermatitis in those who work in the perfume industry or food handlers. Cinnamic aldehyde is contained in the “fragrance mix”.
Cinnamaldehyde is a pale yellow to yellow-green oily liquid with a strong pungent, spicy, cinnamon odor. It is generally insoluble in water and many organic solvents, but is miscible with alcohol and other flavoring oils. Exposure to air will cause thickening and oxidation.


