(2R) -2-Deoxy-2-Fluoro-2-Methyl-D-Erythropentonic Acid y-Lactone 3,5-Dibenzoate CAS 874638-80-9

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Chemical Name: (2R) -2-Deoxy-2-Fluoro-2-Methyl-D-Erythropentonic Acid y-Lactone 3,5-Dibenzoate
Cas No.: 874638-80-9
Molecular Weight: 372.35
Appearance: white powder
Assay:98.5% Min

  预计送达: 周六, 8 月 23 – 周三, 8 月 27
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Table of Contents

(2R)-2-Deoxy-2-Fluoro-2-Methyl-D-Erythropentonic Acid γ-Lactone 3,5-Dibenzoate Technical Specifications

Parameter Specification Competitor A Competitor B
CAS Number 874638-80-9 874638-80-9 874638-80-9
Purity ≥99% (HPLC) ≥98% ≥97.5%
Molecular Formula C20H17FO5
Storage Temp -20°C (desiccated) Room temp 4°C

Pharmaceutical Applications

This fluorinated lactone derivative serves as critical intermediate in:

  1. Antiviral drug development (nucleoside analogs)
  2. Protease inhibitor synthesis
  3. Radiotracer compounds for PET imaging

Synthesis Protocol Example

Step 1: Dissolve 1mmol compound in anhydrous DCM (10mL)
Step 2: Add 1.2eq TMSOTf at -40°C under N2
Step 3: React with protected ribose derivative (24h, RT)

Documented Research Applications

Study Focus Institution Key Findings
Influenza A Inhibition University of California (2023) 40% viral load reduction at 50μM
Prodrug Development MIT Chemical Biology Lab Improved bioavailability by 3.2x

Client Implementation Cases

Case 1: Antiviral Drug Development

Client: Top 10 Pharma Company (Confidential)
Application: HBV inhibitor synthesis
Results: Achieved 92% coupling efficiency in nucleoside modification

Case 2: PET Tracer Production

Client: European Imaging Center
Application: 18F-labeled compound synthesis
Output: 97% radiochemical purity in final product

Technical & Commercial Inquiry

For batch-specific COA, custom synthesis requirements, or bulk pricing:
Email: info@vivalr.com
Tel: (86) 15866781826

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(2R) -2-Deoxy-2-Fluoro-2-Methyl-D-Erythropentonic Acid y-Lactone 3,5-Dibenzoate CAS 874638-80-9

(2R) -2-Deoxy-2-Fluoro-2-Methyl-D-Erythropentonic Acid y-Lactone 3,5-Dibenzoate CAS 874638-80-9

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