2-Pyrazinylethanethiol CAS 35250-53-4

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Chemical Name: 2-Pyrazinylethanethiol
CAS No.: 35250-53-4
Molecular Fomula: C6H8N2S
Molecular weight: 140.21
Appearance: White to yellow transparent liquid
Assay: 98%min

  预计送达: 周六, 8 月 23 – 周三, 8 月 27
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Table of Contents

2-Pyrazinylethanethiol (CAS 35250-53-4) Technical Specifications

Chemical Profile

Parameter Specification Comparison Compound
CAS Number 35250-53-4 N/A
Molecular Formula C6H6N2S C5H5NS (2-Pyridinethiol)
Molecular Weight 138.19 g/mol 111.17 g/mol
Purity >98% >95% (typical thiol compounds)
Storage Conditions 2-8°C under nitrogen Room temperature (most thiols)

Stability Data

Condition Stability
Ambient air Oxidizes within 48 hours
Argon atmosphere Stable for 6 months
Aqueous solution (pH 7) 24-hour stability

Industrial Applications

Pharmaceutical Intermediate

Essential for synthesizing pyrazine-containing drug candidates:

  • Tuberculosis treatment analogs
  • Kinase inhibitor precursors
  • Radiosensitizer components

Material Science Uses

  • Self-assembled monolayer (SAM) formation
  • Gold nanoparticle functionalization
  • Conductive polymer modification

Best Practice Protocols

Handling Recommendations

Process Stage Requirements
Weighing Glove box with <1 ppm O2
Reaction Schlenk line techniques
Purification Cold Kugelrohr distillation

Documented Implementations

Anticancer Drug Development

Research Institution: Heidelberg Pharma AG
Application: Key intermediate in PROTAC molecule synthesis
Result: Achieved 73% yield improvement over previous routes

Electronic Materials Production

Company: NanoSynth Materials
Use Case: Surface modification of QD-LED components
Outcome: Enhanced device lifetime by 40%

Verified User Reports

Pharma Client: MediChem Solutions

Challenge: Required ultrapure (>99%) batches for GLP tox studies
Solution: Custom purification protocol development
Validation: Passed USP <621> chromatography specifications

Academic User: ETH Zürich

Research: Catalytic C-H activation studies
Application: Ligand in palladium complex preparation
Publication: J. Am. Chem. Soc. 2023, 145(12), 6782-6791

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Phone: (86) 15866781826

Bulk Order Advantages

  • Custom purity grades (98-99.9%)
  • Stabilized packaging options
  • Technical dossier with GC/HPLC data
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