Isothiazolinones CAS#26172-55-4
Isothiazolinones are a class of broad-spectrum, highly effective fungicides and biocides, composed of 5-chloro-2-methyl-4-thiazoline-3-one (CMI) and 2-methyl-4-thiazoline-3-one (MI). These compounds are recognized for their rapid action against microbes, inhibiting their growth upon contact and leading to cell death 9. They are characterized by high biocidal efficiency, good degradation, no residual, safe operation, compatibility, stabilization, and low operational costs 9.
Isothiazolinones are used in various industrial applications, including cooling water systems and wastewater treatment in fields such as oil, papermaking, pesticides, cutting oils, leather, detergents, and cosmetics. They are compatible with chlorine and most cationic, anionic, and non-ionic surfactants, and at higher dosages, they exhibit excellent bio-sludge stripping effects 9.
The active content in Isothiazolinones-based products typically ranges from 1.5% to 15%, with a pH value between 1.0 and 5.0, depending on the grade. They are available in various forms such as transparent liquids and are packaged in quantities that can be tailored to specific industrial needs 10. Safety precautions are essential when handling Isothiazolinones due to their corrosive nature; they should not come into contact with skin or eyes, and protective equipment is recommended during use
| Isothiazolinones Chemical Properties |
| Melting point | 42-45?C |
| Boiling point | 109.7??C |
| density | 1.25 (14% aq.) |
| refractive index | n20/D 1.378 |
| storage temp. | Refrigerator |
| solubility | Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly, Heated) |
| form | Liquid |
| pka | -4.06??0.40(Predicted) |
| Stability: | Stable. Incompatible with strong oxidizing agents. |
| LogP | 0.240 (est) |
| CAS DataBase Reference | 26172-55-4(CAS DataBase Reference) |
| NIST Chemistry Reference | 5-Chloro-2-methyl-3(2h)-isothiazolone(26172-55-4) |
| EPA Substance Registry System | 5-Chloro-2-methyl-4-isothiazolin-3-one (26172-55-4) |
| Safety Information |
| Hazard Codes | C,N,T,Xn |
| Risk Statements | 34-43-50-20/21/22-50/53-23/24/25-42/43 |
| Safety Statements | 26-36/37/39-45-60-61-24-28-36/37-23 |
| RIDADR | UN 1760 8/PG 2 |
| WGK Germany | 1 |
| RTECS | NX8156850 |
| HazardClass | 8 |
| PackingGroup | III |
| HS Code | 3808929090 |
| Hazardous Substances Data | 26172-55-4(Hazardous Substances Data) |
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